Publications

Key Pubblications




Cerase A.*,π, Armaos A.*, Neumayer C., Avner P., Guttmanπ, and Tartaglia G.π. Phase separation drives X chromosome Inactivation: a hypothesis πCorrespondent author. Nat. Str. Mol. Bio. 2019 May; 26(5):331-334.

Cirillo D., Blanco M., Armaos A., Buness A., Avner P., Gutmann M., Cerase A* and Tartaglia G.*, Quantitative predictions of protein interactions with long non-coding RNA. Nature Methods, 2016 Dec 29;14(1):5-6 * Correspondent author.

Chen C.K., Blanco M., Jackson C., Aznauryan E., Ollikainen N., Surka C., Chow A., Cerase A., McDonel P., Guttman M. Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing. Science, 2016 Oct 28;354(6311):468-472.

Moindrot B.*, Cerase A.*, Coker H., Masui O., Grizenhout A., Pintacuda G., Schermelleh L., Nesterova T.B., Pintacuta G., Brockdorff N. A pooled shRNA screen identifies Rbm15, Spen and Wtap as factors required for Xist RNA-mediated silencing. Cell Reports, 2015 Jul 28. *First author

Cerase A., Smeets D., Tang Y.A., Gdula M., Kraus F. Spivakov M., Moindrot B., Leleu M., Tattermusch A., Demmerle J., Nesterova T.B., Green C., Otte A.P., Schermelleh L. and Brockdorff N. Spatial separation of Xist-RNA and Polycomb proteins revealed by super resolution microscopy. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2235-40

All publications: Orcid.org

Publication list


Google Scholar
ReserachGate
OrcID
Loop


2019
Cerase A.*, Armaos A.*, Neumayer C., Cid F., Guttman M., Avner P. and Tartaglia G.*. Phase separation drives X chromosome Inactivation: a hypothesis * Correspondent author. First version of the manuscript deposited in BiorXiv (https://www.biorxiv.org/content/early/2018/06/20/351015). Nat. Str. Mol. Bio. 2019 May; 26(5):331-334.

Gartler S.M, Goldaman M.A., Cerase A. The Xist Locus. Book chapter. Reference Module in Life Sciences, Elsevier. Online.

2018
Cerase Andrea. Awakening the Sleeping Giant: methods to reactivate the inactive X Chromosome as clinical treatment for X -linked disorders. Journal of Translational Genetics and Genomics. Editorial, March 1st 2018.

Pintacuda G*, Young A.N. and Cerase A*. Function by structure: Spotlights on Xist RNA. Review. Inaugural paper for Frontiers in Molecular Biosciences (invited), Dec. 19th 2017. *Correspondent author.

2017
Pintacuda G., Wei G., Roustan C., Anil-Kirmitzas B., Solcan N., Cerase A., Castello A., Shabaz M., Moindrot B., Nesterova T., Brockdorff N. hnRNPK recruits PCGF3/5-PRC1 to the Xist RNA B-repeat to establish Polycomb-mediated chromosomal silencing. Mol. Cell, December 7th 2017.

Almeida M., Pintacuda G., Masui O., Koseki Y., Gdula M, Cerase A., Brown D., Mould A., Innocent C., Nakayama M., Shermelleh L., Nesterova T., Koseki H, and Brockdorff N. PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation. Science, Jun 9 2017;356(6342.

2016
Cirillo D., Blanco M., Armaos A., Buness A., Avner P., Gutmann M., Cerase A* and Tartaglia G.*, Quantitative predictions of protein interactions with long non-coding RNA. Nature Methods, 2016 Dec 29;14(1):5-6 * Correspondent author.

Chen C.K., Blanco M., Jackson C., Aznauryan E., Ollikainen N., Surka C., Chow A., Cerase A., McDonel P., Guttman M. Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing. Science, 2016 Oct 28;354(6311):468-472. Epub 2016 Aug 4.

Cerase A. X chromosome inactivation: The Importance of being inactive. Seminars in Cell and Developmental Biology, Vol 56, Aug. 2016. Editorial for a special issue on X Chromosome Inactivation. *Correspondent author.

2015
Pintacuta G. and Cerase A. * X inactivation lessons from differentiating embryonic stem cells. Cell Reviews and Reports, 2015 Oct;11(5):699-705 *Correspondent author.

Cerase A.*, Pintacuta G., Tattermusch A. and Avner P. Xist localization and function: New insights from multiple levels. Genome Biology, 2015 Aug 15;16:166 * Co-correspondent author.

Moindrot B., Cerase A.*, Coker H., Masui O., Grizenhout A., Pintacuda G., Schermelleh L., Nesterova T.B., Pintacuta G., Brockdorff N. A pooled shRNA screen identifies Rbm15, Spen and Wtap as factors required for Xist RNA-mediated silencing. Cell Reports, 2015 Jul 28. *Co-first author.

2014
Smeets D., Markaki Y., Volker J. Schmid, Felix Kraus, Tattermusch A., Cerase A., Sterr, M., Fielder S., Demmerle J., Popken J., Leonhardt H., Brockdorff N., Cremer T., Schermelleh L., Cremer M. Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci. Epigenetics&Chromatin, 2014 Apr 28;7:8.

Cerase A., Smeets D., Tang Y.A., Gdula M., Kraus F. Spivakov M., Moindrot B., Leleu M., Tattermusch A., Demmerle J., Nesterova T.B., Green C., Otte A.P., Schermelleh L. and Brockdorff N. Spatial separation of Xist-RNA and Polycomb proteins revealed by super resolution microscopy. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2235-40.

2012
Farcas A.M., Blackledge N.P., Sudbery I., Long H.K., McGouran J.F., Rose N.R., Lee S., Sims D., Cerase A., Sheahan T., Koseki H., Brockdorff N., Ponting C., Kessler B.M., J Klose R.J. KDM2B links the Polycomb Repressive Complex 1 (PRC1) to recognition of CpG islands. Elife. 2012 Dec 18;1:e00205.

2011
Casanova M. *, Preissner T. *, Cerase A.#, Poot R., Yamada D., Li X., Appanah R., Bezstarosti K., Demmers J., Koseki H. and Brockdorff N. Polycomblike 2 facilitates recruitment of PRC2 Polycomb-group complexes to the inactive X chromosome and to target loci in ES cells. Development. 2011 Apr;138(8):*equal contribution. #Second author.

2010
Tang Y.A., Huntley D., Montana G., Cerase A., Nesterova T.B., and Brockdorff N. Xist mediated silencing on autosomes is linked to chromosomal domain organization. Epigenetics&Chromatin. 2010 May;3(1):10.

2008
Matarazzo M.R., Cerase A. and D’Esposito, M. Building up the inactive X chromosome. Biol Cell. 2008 Jan;100(1):63-70.

2007
Matarazzo M.R.*, De Bonis M.L.*, Strazzullo M.*, Cerase A.#, Ferraro M.,Vastarelli P., Ballestar E., Esteller M., Kudo S., and M. D’Esposito. Multiple binding of methyl-CpG and polycomb proteins in long-term gene silencing events. Jounal of Cell Physiology 2007 Mar;2010(3):711-9. *Equal contribution, #Second author.

2006
De Bonis M.L., Cerase A.*, Matarazzo M.R., Ferraro M., Strazzullo,M., Hansen R.S. , Chiurazzi P, Neri G. and M. D'Esposito. Maintenance of X-and Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications. Human Molecular Genetics 2006 Apr 1;15(7):1123-32. *Co-first author.

2003
Strazzullo M., Cossu A., Baldinu P., Colombino M., Satta M.P., Tanda F., De Bonis M.L., Cerase A., D'Urso M., D'Esposito M., Palmieri G. High-resolution methylation analysis of the hMLH1 promoter in sporadic endometrial and colorectal carcinomas. Cancer 2003 Oct 1;98(7):1540-6.

Unpublished results/reagents and projects at: www.researchgate.net - Andrea Cerase